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Rebound-associated vertebral fractures after denosumab discontinuation in a lung cancer patient with bone metastases

Denosumab is a commonly used antiresorptive treatment in patients with osteoporosis or solid tumours with bone metastases. Upon denosumab discontinuation, a rebound phenomenon can occur that results in an increased (vertebral) fracture risk. This phenomenon is well-known in the setting of osteoporos...

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Principais autores: Jolan Dupont, Wesley Appermans, Marian Dejaeger, Isabelle Wauters, Michaël R. Laurent, Evelien Gielen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-06-01
Serier:Bone Reports
Fag:
Bone turnover markers
Denosumab
Osteoporosis
Vertebral fractures
Rebound phenomenon
Online adgang:http://www.sciencedirect.com/science/article/pii/S2352187222004168
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