Magnetic targeting enhances the neuroprotective function of human mesenchymal stem cell-derived iron oxide exosomes by delivering miR-1228-5p

Abstract Background Treating mitochondrial dysfunction is a promising approach for the treatment of post-stroke cognitive impairment (PSCI). HuMSC-derived exosomes (H-Ex) have shown powerful therapeutic effects in improving mitochondrial function, but the specific effects are unclear and its brain t...

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Hlavní autoři:	Wei-Jia Hu, Hong Wei, Li-Li Cai, Yu-Hao Xu, Rui Du, Qun Zhou, Xiao-Lan Zhu, Yue-Feng Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-10-01
Edice:	Journal of Nanobiotechnology
Témata:	Exosomes Oxidative stress Cognitive impairment Superparamagnetic iron oxide nanoparticles
On-line přístup:	https://doi.org/10.1186/s12951-024-02941-3
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