Exosome-enabled bone defect repair: mechanistic foundations, bioengineered delivery, and artificial intelligence-driven translation

Abstract Bone defects remain a substantial clinical burden. Exosomes have been extensively investigated as cell-free therapeutic candidates, exhibiting favorable biocompatibility and potential applicability in bone defect repair. Mechanisms relevant to bone regeneration are delineated, including act...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Shen Yang, Siliang Ge, Zhongyang Liu, Junyu Chen, Feifan Chang, Junmin Shen, Fanfeng Wu, Xinyu Sun, Zhongqi Wang, Yi Li, Mingming Zhang, Ruijing Chen, Taojin Feng, Tao Yin, Pincong Fu, Ming Chen, Pengbin Yin, Libo Hao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-03-01
Schriftenreihe:	Journal of Nanobiotechnology
Schlagworte:	Exosomes Bone defect repair Bioengineered delivery systems Biomaterials Artificial intelligence Translational medicine
Online-Zugang:	https://doi.org/10.1186/s12951-026-04176-w
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