Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity

Summary: RNA-binding protein aggregation is a pathological hallmark of several neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). To gain better insight into the molecular interactions underlying this process, we investigated FUS,...

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Үндсэн зохиолчид:	Elke Bogaert, Steven Boeynaems, Masato Kato, Lin Guo, Thomas R. Caulfield, Jolien Steyaert, Wendy Scheveneels, Nathalie Wilmans, Wanda Haeck, Nicole Hersmus, Joost Schymkowitz, Frederic Rousseau, James Shorter, Patrick Callaerts, Wim Robberecht, Philip Van Damme, Ludo Van Den Bosch
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2018-07-01
Цуврал:	Cell Reports
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2211124718309975
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!