High transconjugation efficiency of fusion plasmid pNDM_KPC in carbapenem-resistant Citrobacter freundii and its formation driven by IS26-mediated integration

ABSTRACT Carbapenem-resistant Enterobacteriales (CRE) are increasingly recognized as reemerging nosocomial pathogens due to the dissemination of dual carbapenemase production. This study investigates the coexistence of blaKPC-2 and blaNDM-1 in CRE isolates, harbored on plasmids either separately and...

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Detalhes bibliográficos

Principais autores:	Yuxiaoting Li, Xinhong Han, Xiangping Shi, Caiping Mao, Ting Yu, Yufeng Zhu, Shengjun Wu, Youping Huang, Yunsong Yu, Ying Fu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2025-10-01
coleção:	Microbiology Spectrum
Assuntos:	Carbapenem-resistant Citrobacter freundii pNDM_KPC NDM-1 KPC-2 IS26
Acesso em linha:	https://journals.asm.org/doi/10.1128/spectrum.00905-25
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