Dissecting the basis for differential substrate specificity of ADAR1 and ADAR2
Abstract Millions of adenosines are deaminated throughout the transcriptome by ADAR1 and/or ADAR2 at varying levels, raising the question of what are the determinants guiding substrate specificity and how these differ between the two enzymes. We monitor how secondary structure modulates ADAR2 vs ADA...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Portfolio
2023-12-01
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| Серии: | Nature Communications |
| Online-ссылка: | https://doi.org/10.1038/s41467-023-43633-0 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
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