A comprehensive evaluation of microbial differential abundance analysis methods: current status and potential solutions

Abstract Background Differential abundance analysis (DAA) is one central statistical task in microbiome data analysis. A robust and powerful DAA tool can help identify highly confident microbial candidates for further biological validation. Numerous DAA tools have been proposed in the past decade ad...

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Detalhes bibliográficos

Principais autores:	Lu Yang, Jun Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-08-01
Colecção:	Microbiome
Assuntos:	Microbiome Metagenomics Statistical methods Differential abundance analysis False discovery rate Compositional effects
Acesso em linha:	https://doi.org/10.1186/s40168-022-01320-0
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