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Structural insights into G protein-coupled receptor signaling

G protein-coupled receptors (GPCRs) are the largest single family of transmembrane proteins encoded in the human genome, and they are among the most successful classes of therapeutic drug targets of all time. Signaling by GPCRs relies on an intricate relay of conformational changes that can be induc...

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Hlavní autor: Andrew Kruse
Médium: Artigo
Jazyk:Inglês
Vydáno: AIP Publishing LLC and ACA 2025-10-01
Edice:Structural Dynamics
On-line přístup:https://pubs.aip.org/aca/sdy/article-pdf/12/5_Supplement/A208/20775677/a208_1_4.0000998.pdf
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