Discovery of Two Inhibitors of the Type IV Pilus Assembly ATPase PilB as Potential Antivirulence Compounds

ABSTRACT With the pressing antibiotic resistance pandemic, antivirulence has been increasingly explored as an alternative strategy against bacterial infections. The bacterial type IV pilus (T4P) is a well-documented virulence factor and an attractive target for small molecules for antivirulence purp...

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Egile Nagusiak:	Keane J. Dye, Nancy J. Vogelaar, Megan O’Hara, Pablo Sobrado, Webster Santos, Paul R. Carlier, Zhaomin Yang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology 2022-12-01
Saila:	Microbiology Spectrum
Gaiak:	antivirulence PilB ATPase type IV pilus T4P assembly high-throughput screen benserazide
Sarrera elektronikoa:	https://journals.asm.org/doi/10.1128/spectrum.03877-22
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