APOE ε4 Allele Dose and Time to Clinical Conversion from Mild Cognitive Impairment to Alzheimer’s Disease Dementia: An ADNI Survival Analysis

<b>Background/Objectives:</b> Existing Alzheimer’s disease (AD) prediction studies often treat APOE ε4 as a binary carrier variable and emphasize classification rather than time-to-event progression. This study evaluated whether APOE ε4 allele dose predicts clinical conversion from mild cognitive im...

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Detalles Bibliográficos

Principais autores:	Faizaan Fazal Khan, Goo-Rak Kwon
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2026-06-01
Series:	Biomedicines
Assuntos:	Alzheimer disease mild cognitive impairment apolipoprotein E4 disease progression survival analysis proportional hazards models
Acceso en liña:	https://www.mdpi.com/2227-9059/14/6/1280
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