Flexible analysis of spatial transcriptomics data (FAST): a deconvolution approach

Abstract Motivation Spatial transcriptomics is a state-of-art technique that allows researchers to study gene expression patterns in tissues over the spatial domain. As a result of technical limitations, the majority of spatial transcriptomics techniques provide bulk data for each sequencing spot. C...

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Detalles Bibliográficos

Autores principales:	Meng Zhang, Joel Parker, Lingling An, Yiwen Liu, Xiaoxiao Sun
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-01-01
Colección:	BMC Bioinformatics
Materias:	Spatial transcriptomics Reference-free Deconvolution Non-negative matrix factorization
Acceso en línea:	https://doi.org/10.1186/s12859-025-06054-y
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