क्यूआर कोड

Development and In Vitro Evaluation of Controlled Release Viagra<sup>®</sup> Containing Poloxamer-188 Using Gastroplus<sup>™</sup> PBPK Modeling Software for In Vivo Predictions and Pharmacokinetic Assessments

Sildenafil is the active substance in Viagra<sup>®</sup> tablets, which is approved by the FDA to treat sexual dysfunction in men. Poor solubility and short half-life, however, can limit the span of its effectiveness. Therefore, this study focused on an oral controlled release matrix system with the...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Mosab Arafat, Muhammad Sarfraz, Salahdein AbuRuz
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2021-05-01
श्रृंखला:Pharmaceuticals
विषय:
sildenafil citrate
poloxamer-188
matrix system
polymer
controlled release
ऑनलाइन पहुंच:https://www.mdpi.com/1424-8247/14/5/479
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