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Evaluation of allelic expression of imprinted genes in adult human blood.

Imprinted genes are expressed from only one allele in a parent-of-origin dependent manner. Loss of imprinted (LOI) expression can result in a variety of human disorders and is frequently reported in cancer. Biallelic expression of imprinted genes in adult blood has been suggested as a useful biomark...

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Autori principali: Jennifer M Frost, Dave Monk, Taita Stojilkovic-Mikic, Kathryn Woodfine, Lyn S Chitty, Adele Murrell, Philip Stanier, Gudrun E Moore
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2010-10-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC2958851?pdf=render
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