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Computational studies of pyrimidine derivatives as inhibitors of human σ1 receptor using 3D-QSAR analysis, molecular docking, ADMET properties and DFT investigation

Neuropathic pain syndrome has a profoundly negative and agonizing impact on the lives of the individuals it afflicts. In order to find an effective treatment for this condition, extensive and thorough scientific studies have demonstrated that the σ1 receptor serves as an exceptional target for thera...

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Autores principales: Maroua Fattouche, Salah Belaidi, Mebarka Ouassaf, Samir Chtita, Muneerah Mogren Al-Mogren, Majdi Hochlaf
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2024-06-01
Colección:Chemical Physics Impact
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2667022424000070
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