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Integrative Approach for Designing Novel Triazole Derivatives as α-Glucosidase Inhibitors: QSAR, Molecular Docking, ADMET, and Molecular Dynamics Investigations

In response to the increasing prevalence of diabetes mellitus and the limitations associated with the current treatments, there is a growing need to develop novel medications for this disease. This study is focused on creating new compounds that exhibit a strong inhibition of alpha-glucosidase, whic...

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Autores principales: Oussama Abchir, Meriem Khedraoui, Hassan Nour, Imane Yamari, Abdelkbir Errougui, Abdelouahid Samadi, Samir Chtita
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2024-02-01
Colección:Pharmaceuticals
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Acceso en línea:https://www.mdpi.com/1424-8247/17/2/261
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