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NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway

BackgroundAge-related decline in nicotinamide adenine dinucleotide (NAD+)—a central regulator of cellular metabolism, DNA repair, and immune homeostasis—is strongly associated with physiological dysfunction. Nicotinamide mononucleotide (NMN), a potent NAD+ precursor, shows promise in counteracting a...

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主要な著者: Yuxian Lin, Yajing Wang, Xinxin Yang, Ziwei Ding, Mingye Hu, Xianfeng Huang, Qichun Zhang, Yingcong Yu
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2025-04-01
シリーズ:Frontiers in Pharmacology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fphar.2025.1545585/full
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