NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway

BackgroundAge-related decline in nicotinamide adenine dinucleotide (NAD+)—a central regulator of cellular metabolism, DNA repair, and immune homeostasis—is strongly associated with physiological dysfunction. Nicotinamide mononucleotide (NMN), a potent NAD+ precursor, shows promise in counteracting a...

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Bibliografische Detailangaben

Hauptverfasser:	Yuxian Lin, Yajing Wang, Xinxin Yang, Ziwei Ding, Mingye Hu, Xianfeng Huang, Qichun Zhang, Yingcong Yu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-04-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	aging NMN oxidative stress neuroinflammation intestinal barrier SIRT1
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1545585/full
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