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The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma

Galangin (GG), a flavonoid, elicits a potent antitumor activity in diverse cancers. Here, we evaluated the efficacy of GG in the treatment of human glioblastoma multiforme (GBM) and investigated the molecular basis for its inhibitory effects in the disease. GG inhibited viability and proliferation o...

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Principais autores: Yang Kong, Zichao Feng, Anjing Chen, Qichao Qi, Mingzhi Han, Shuai Wang, Yulin Zhang, Xin Zhang, Ning Yang, Jiwei Wang, Bin Huang, Qing Zhang, Guo Xiang, Wenjie Li, Di Zhang, Jian Wang, Xingang Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-09-01
Serier:Frontiers in Oncology
Fag:
apoptosis
autophagy
galangin
pyroptosis
glioblastoma
Online adgang:https://www.frontiersin.org/article/10.3389/fonc.2019.00942/full
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