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A specific, stable, and accessible LAMP assay targeting the HSP70 gene of Trypanosoma cruzi

ABSTRACT Diagnostic delays prevent most Chagas disease patients from receiving timely therapy during the acute phase when treatment is effective. Quantitative PCR (qPCR)-based diagnostic methods provide high sensitivity during this phase but require specialized equipment and complex protocols. More...

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Principais autores: Sneider Alexander Gutierrez Guarnizo, Beth Jessy Condori, Luciana Basma, Shirley Equilia, Edith Malaga, Siena Defazio, Emily Arteaga, Jean Karla Velarde, Martín Obregón, Anshule Takyar, Carolina Duque, Jill Hakim, Freddy Tinajeros, Robert H. Gilman, Natalie Bowman, Monica R. Mugnier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2025-11-01
coleção:Microbiology Spectrum
Assuntos:
molecular diagnosis
LAMP-PCR
cost-effective method
HSP70 gene
acute chagas
congenital transmission
Acesso em linha:https://journals.asm.org/doi/10.1128/spectrum.00172-25
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