Parthanatos drives cognitive decline in repeated brain trauma: MSC-derived exosomes as a novel therapeutic strategy

IntroductionRepetitive traumatic brain injury (RTBI) represents a cumulative neurological insult associated with progressive neurodegeneration and limited therapeutic options. In this study, we uniquely evaluate the neuroprotective potential of mesenchymal stem cell (MSC)-derived exosomes in a rat m...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Heba Mohammed Refat M. Selim, Amira A. El-Gazar, Dalaal M. Abdallah, Hagar B. Abo-Zalam, Ghada M. Ragab, Ahmed N. Abdallah, Rabab A. El-Gazar, Sultan Alshehri, Einas M. Yousef, Rayan Ballal, Sahar N. Aljarallah, Asmaa Saleh, Nada F. Abou Chahin, Naheda S. Alsammak, Rasha A. Mandil, Hanan S. El-Abhar
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2025-09-01
Σειρά:	Frontiers in Pharmacology
Θέματα:	exosomes parthanatos cyclophilin B PARP1 calpain oxidative stress
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1622018/full
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