p53 status determines the epigenetic response to demethylating agents azacitidine and decitabine

Abstract 5’-Azacitidine (Aza) and 5-Aza-2’-deoxycytidine (Dac) are widely used demethylating drugs that directly integrate into nucleic acids. They are frequently used interchangeably, surprisingly as their selectivity is unique from the other, with no predictors of response or clinical biomarkers t...

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Үндсэн зохиолчид:	Emma Langdale Hands, Arndt Wallmann, Gabrielle Oxley, Sophie Storrar, Rochelle D’Souza, Mathew Van de Pette
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer Nature 2026-01-01
Цуврал:	EMBO Reports
Нөхцлүүд:	R-Loops p53 Epigenetics Azacitidine Decitabine
Онлайн хандалт:	https://doi.org/10.1038/s44319-025-00678-0
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!