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ATP6AP2, a regulator of LRP6/β-catenin protein trafficking, promotes Wnt/β-catenin signaling and bone formation in a cell type dependent manner

Abstract Wnt/β-catenin signaling is critical for various cellular processes in multiple cell types, including osteoblast (OB) differentiation and function. Exactly how Wnt/β-catenin signaling is regulated in OBs remain elusive. ATP6AP2, an accessory subunit of V-ATPase, plays important roles in mult...

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Principais autores: Lei Xiong, Hao-Han Guo, Jin-Xiu Pan, Xiao Ren, Daehoon Lee, Li Chen, Lin Mei, Wen-Cheng Xiong
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2024-05-01
סדרה:Bone Research
גישה מקוונת:https://doi.org/10.1038/s41413-024-00335-7
תגים: הוספת תג
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