Potential of Murine IgG1 and Human IgG4 to Inhibit the Classical Complement and Fcγ Receptor Activation Pathways

IgG antibodies (Abs) mediate their effector functions through the interaction with Fcγ receptors (FcγRs) and the complement factors. The main IgG-mediated complement activation pathway is induced through the binding of complement C1q to IgG Abs. This interaction is dependent on antigen-dependent hex...

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Principais autores:	Gina-Maria Lilienthal, Johann Rahmöller, Janina Petry, Yannic C. Bartsch, Alexei Leliavski, Marc Ehlers
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2018-05-01
סדרה:	Frontiers in Immunology
נושאים:	complement C1q IgG4 IgG IgG hexamer IgG glycosylation
גישה מקוונת:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00958/full
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