The Role of Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis
The Hedgehog (Hh)-glioma-associated oncogene homolog (GLI) signaling pathway is highly conserved among mammals, with crucial roles in regulating embryonic development as well as in cancer initiation and progression. The GLI transcription factors (GLI1, GLI2, and GLI3) are effectors of the Hh pathway...
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| Автори: | , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2021-09-01
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| Серія: | Biomedicines |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/2227-9059/9/9/1188 |
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