Generation of a Syngeneic Heterozygous <i>ACVRL1<sup>(wt/mut)</sup></i> Knockout iPS Cell Line for the In Vitro Study of HHT2-Associated Angiogenesis
Hereditary hemorrhagic telangiectasia (HHT) type 2 is an autosomal dominant disease in which one allele of the <i>ACVRL1</i> gene is mutated. Patients exhibit disturbances in TGF-beta/BMP-dependent angiogenesis and, clinically, often present with severe nosebleeds as well as a reduced quality of lif...
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| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI AG
2023-06-01
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| Seri Bilgileri: | Cells |
| Konular: | |
| Online Erişim: | https://www.mdpi.com/2073-4409/12/12/1600 |
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