Generation of a Syngeneic Heterozygous <i>ACVRL1^(wt/mut)</i> Knockout iPS Cell Line for the In Vitro Study of HHT2-Associated Angiogenesis

Hereditary hemorrhagic telangiectasia (HHT) type 2 is an autosomal dominant disease in which one allele of the <i>ACVRL1</i> gene is mutated. Patients exhibit disturbances in TGF-beta/BMP-dependent angiogenesis and, clinically, often present with severe nosebleeds as well as a reduced quality of lif...

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Auteurs principaux:	Li Xiang-Tischhauser, Michael Bette, Johanna R. Rusche, Katrin Roth, Norio Kasahara, Boris A. Stuck, Udo Bakowsky, Maria Wartenberg, Heinrich Sauer, Urban W. Geisthoff, Robert Mandic
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2023-06-01
Collection:	Cells
Sujets:	Morbus Osler HHT2 ACVRL1 iPSC
Accès en ligne:	https://www.mdpi.com/2073-4409/12/12/1600
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