Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines

The incidence of head and neck squamous cell carcinoma (HNSCC) is increasing and the conventional treatments for this form of cancer can be tough. Despite the success of existing immunotherapies in some HNSCC patients, many do not respond to this type of treatment. Thus, the development of novel ant...

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Hlavní autoři:	Susannah von Hofsten, Manuel K. Langer, Katja Korelin, Synnøve Magnussen, Dominik Ausbacher, Trude Anderssen, Tuula Salo, Morten B. Strøm, Annette Bayer, Ahmed Al-Samadi, Gerd Berge
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-03-01
Edice:	Frontiers in Pharmacology
Témata:	cancer lysosomotropic calreticulin immunogenic cell death head and neck squamous cell cancer (HNSCC) drug development
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1141669/full
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