4-nitroquinoline 1-oxide-induced oral epithelial lesions exhibit time- and stage-dependent changes in the tumor immune microenvironment

Oral tongue squamous cell carcinoma (OTSCC) is the most common cancer of the oral cavity and is associated with high morbidity due to local invasion and lymph node metastasis. Tumor infiltrating lymphocytes (TILs) are associated with good prognosis in oral cancer patients and dictate response to tre...

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Bibliographic Details

Main Authors:	Kjersti Sellæg, Ruth Schwienbacher, Mathias Kranz, Anna Engan Aamodt, Anna M. Wirsing, Gerd Berge, Elin Hadler-Olsen, Synnøve Norvoll Magnussen
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2024-05-01
Series:	Frontiers in Oncology
Subjects:	4-nitroquinoline 1-oxide (4NQO) tumor infiltrating lymphocytes (TILs) high endothelial venules (HEVs) tumor microenvironment tertiary lymphoid structures (TLS) oral carcinogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1343839/full
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