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DNA Binding Studies of Vinca Alkaloids: Experimental and Computational Evidence

Fluorescence studies on the indole alkaloids vinblastine sulfate, vincristine sulfate, vincamine and catharanthine have demonstrated the DNA binding ability of these molecules. The binding mode of these molecules in the minor groove of DNA is non-specific. A new parameter of the purine-pyrimidine ba...

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Váldodahkkit: Prateek Pandya, Surendra P. Gupta, Kumud Pandav, Ritu Barthwal, B. Jayaram, Surat Kumar
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: SAGE Publishing 2012-03-01
Ráidu:Natural Product Communications
Liŋkkat:https://doi.org/10.1177/1934578X1200700308
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