In Vitro-Reconstituted Nucleoids Can Block Mitochondrial DNA Replication and Transcription

The mechanisms regulating the number of active copies of mtDNA are still unclear. A mammalian cell typically contains 1,000–10,000 copies of mtDNA, which are packaged into nucleoprotein complexes termed nucleoids. The main protein component of these structures is mitochondrial transcription factor A...

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Detalhes bibliográficos

Principais autores:	Géraldine Farge, Majda Mehmedovic, Marian Baclayon, Siet M.J.L. van den Wildenberg, Wouter H. Roos, Claes M. Gustafsson, Gijs J.L. Wuite, Maria Falkenberg
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2014-07-01
coleção:	Cell Reports
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124714004409
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