Pheno-SELEX: Engineering Anti-Metastatic Aptamers through Targeting the Invasive Phenotype Using Systemic Evolution of Ligands by Exponential Enrichment

Multiple methods (e.g., small molecules and antibodies) have been engineered to target specific proteins and signaling pathways in cancer. However, many mediators of the cancer phenotype are unknown and the ability to target these phenotypes would help mitigate cancer. Aptamers are small DNA or RNA...

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Opis bibliograficzny

Główni autorzy:	Greg Shelley, Jinlu Dai, Jill M. Keller, Evan T. Keller
Format:	Artigo
Język:	Inglês
Wydane:	MDPI AG 2021-12-01
Seria:	Bioengineering
Hasła przedmiotowe:	aptamer prostate cancer metastasis invasion osteosarcoma murine model
Dostęp online:	https://www.mdpi.com/2306-5354/8/12/212
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