Precision in Tear Fluid Biomarker Discovery: Quantitative Proteomic Profiling of Small-Volume, Individual Samples Using Capillary Tube Collection

<b>Background</b>: Tear fluid, rich in proteins, is a promising source of novel biomarkers for ocular and systemic health. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is the primary method for biomarker discovery. Still, factors such as limited sample volume, extracellular protein cont...

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Autori principali:	Kyla Frenia, Yunxiang Fu, Maria A. Beatty, Kathleen C. Garwood, Jeremy Kimmel, Veena Raiji, Dipanjan Pan, David Bartlett, Leanne T. Labriola, Kunhong Xiao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-02-01
Serie:	Biomedicines
Soggetti:	tear proteomics tear biomarker biomarker discovery capillary collection LC-MS/MS
Accesso online:	https://www.mdpi.com/2227-9059/13/2/386
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