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Precision in Tear Fluid Biomarker Discovery: Quantitative Proteomic Profiling of Small-Volume, Individual Samples Using Capillary Tube Collection

<b>Background</b>: Tear fluid, rich in proteins, is a promising source of novel biomarkers for ocular and systemic health. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is the primary method for biomarker discovery. Still, factors such as limited sample volume, extracellular protein cont...

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Principais autores: Kyla Frenia, Yunxiang Fu, Maria A. Beatty, Kathleen C. Garwood, Jeremy Kimmel, Veena Raiji, Dipanjan Pan, David Bartlett, Leanne T. Labriola, Kunhong Xiao
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-02-01
Serier:Biomedicines
Fag:
tear proteomics
tear biomarker
biomarker discovery
capillary collection
LC-MS/MS
Online adgang:https://www.mdpi.com/2227-9059/13/2/386
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