Allosteric modulation of G protein-coupled receptor signaling

G protein-coupled receptors (GPCRs), the largest family of transmembrane proteins, regulate a wide array of physiological processes in response to extracellular signals. Although these receptors have proven to be the most successful class of drug targets, their complicated signal transduction pathwa...

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Principais autores:	Siyuan Shen, Chang Zhao, Chao Wu, Suyue Sun, Ziyan Li, Wei Yan, Zhenhua Shao
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2023-02-01
Serija:	Frontiers in Endocrinology
Teme:	G protein-coupled receptors (GPCRs) allosteric modulator structural investigations GPCR signaling regulation allosteric drug discovery
Online dostop:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1137604/full
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