Allosteric Modulators of G Protein-Coupled Dopamine and Serotonin Receptors: A New Class of Atypical Antipsychotics

Schizophrenia was first described by Emil Krapelin in the 19th century as one of the major mental illnesses causing disability worldwide. Since the introduction of chlorpromazine in 1952, strategies aimed at modifying the activity of dopamine receptors have played a major role for the treatment of s...

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Hlavní autoři:	Irene Fasciani, Francesco Petragnano, Gabriella Aloisi, Francesco Marampon, Marco Carli, Marco Scarselli, Roberto Maggio, Mario Rossi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-11-01
Edice:	Pharmaceuticals
Témata:	dopamine receptor serotonin (5-HT) receptor positive allosteric modulator negative allosteric modulator endogenous allosteric modulator allosteric binding site
On-line přístup:	https://www.mdpi.com/1424-8247/13/11/388
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