CD2 targeted nanoparticles containing IL-2 mimic fetal-maternal tolerance of pregnancy by inducing synergistic TGF-β-producing NK cells and Tregs
T regulatory cells (Tregs) are essential for maintaining immune homeostasis and tolerance. We have reported that CD2-targeted nanoparticles containing IL-2 induce CD4 and CD8 Foxp3+ Tregs, together with TGF-β-producing CD56bright NK cells. Generation and maintenance of stable Tregs critically depend...
Zapisane w:
| Główni autorzy: | , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2025-11-01
|
| Seria: | Frontiers in Immunology |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1692547/full |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|