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Spatially coordinated collective phosphorylation filters spatiotemporal noises for precise circadian timekeeping

Summary: The circadian (∼24h) clock is based on a negative-feedback loop centered around the PERIOD protein (PER), translated in the cytoplasm and then enters the nucleus to repress its own transcription at the right time of day. Such precise nucleus entry is mysterious because thousands of PER mole...

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Detaylı Bibliyografya
Asıl Yazarlar: Seok Joo Chae, Dae Wook Kim, Seunggyu Lee, Jae Kyoung Kim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2023-04-01
Seri Bilgileri:iScience
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2589004223006314
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