Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.
Organoid cultures derived from colorectal cancer (CRC) samples are increasingly used as preclinical models for studying tumor biology and the effects of targeted therapies under conditions capturing in vitro the genetic make-up of heterogeneous and even individual neoplasms. While 3D cultures are in...
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| Автори: | , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Public Library of Science (PLoS)
2019-03-01
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| Серія: | PLoS Genetics |
| Онлайн доступ: | http://europepmc.org/articles/PMC6457557?pdf=render |
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