Identification of novel CYP2D7-2D6 hybrids: non-functional and functional variants
Polymorphic expression of CYP2D6 contributes to the wide range of activity observed for this clinically important drug metabolizing enzyme. In this report we describe novel CYP2D7/2D6 hybrid genes encoding non-functional and functional CYP2D6 protein and a CYP2D7 variant that mimics a CYP2D7/2D6 hyb...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2010-10-01
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| Collection: | Frontiers in Pharmacology |
| Sujets: | |
| Accès en ligne: | http://journal.frontiersin.org/Journal/10.3389/fphar.2010.00121/full |
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