Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections
MASP-2, mannose-binding protein-associated serine protease 2, is a key enzyme in the lectin pathway of complement activation. Hyperactivation of this protein by human coronaviruses SARS-CoV, MERS-CoV and SARS-CoV-2 has been found to contribute to aberrant complement activation in patients, leading t...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI AG
2021-02-01
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| Sarja: | Viruses |
| Aiheet: | |
| Linkit: | https://www.mdpi.com/1999-4915/13/2/312 |
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