Recombinant BCG: Innovations on an old vaccine. Scope of BCG strains and strategies to improve long lasting memory

BCG (Bacille Calmette-Guérin), an attenuated vaccine derived from Mycobacterium bovis, is the current vaccine of choice against tuberculosis (TB). Despite its protection against active TB in children, BCG has failed to protect adults against TB infection and active disease development, especially in...

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Autores principales:	Adeliane C da Costa, Sarah Veloso Nogueira, André eKipnis, Ana Paula eJunqueira-Kipnis
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2014-04-01
Colección:	Frontiers in Immunology
Materias:	Memory, Long-Term Tuberculosis protection strain differences rBCG
Acceso en línea:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00152/full
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