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Conditional Fgfr1 Deletion in GnRH Neurons Leads to Minor Disruptions in the Reproductive Axis of Male and Female Mice

In humans and mice, inactivating mutations in fibroblast growth factor receptor 1 (Fgfr1) lead to gonadotropin-releasing hormone (GnRH) deficiency and a host of downstream reproductive disorders. It was unclear if Fgfr1 signaling directly upon GnRH neurons critically drove the establishment of a fun...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Cynthia Dela Cruz, Cassandra A. Horton, Kelsey N. Sanders, Nathan D. Andersen, Pei-San Tsai
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2021-02-01
Rangatū:Frontiers in Endocrinology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fendo.2020.588459/full
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