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Understanding the biology of antigen cross-presentation for the design of vaccines against cancer

Antigen cross-presentation, the process in which exogenous antigens are presented on MHC class I molecules, is crucial for the generation of effector CD8+ T cell responses. Although multiple cell types are being described to be able to cross-present antigens, in vivo this task is mainly carried out...

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Principais autores: Cynthia M. Fehres, Wendy W.J. Unger, Juan J. eGarcia-Vallejo, Yvette eVan Kooyk
格式: Artigo
语言:Inglês
出版: Frontiers Media S.A. 2014-04-01
丛编:Frontiers in Immunology
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在线阅读:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00149/full
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