Endoplasmic reticulum-translocation is essential for APOL1 cellular toxicity

Summary: Two variants at the APOL1 gene, encoding apolipoprotein L1, account for more than 70% of the increased risk for chronic kidney disease in individuals of African ancestry. While the initiating event for APOL1 risk variant cell injury remains to be clarified, we explored the possibility of bl...

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Bibliografske podrobnosti

Principais autores:	Etty Kruzel-Davila, Ira Bavli-Kertselli, Ayala Ofir, Amber M. Cheatham, Revital Shemer, Eid Zaknoun, Sergiy Chornyy, Orly Tabachnikov, Shamara E. Davis, Atanu K. Khatua, Karl Skorecki, Waldemar Popik
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2022-01-01
Serija:	iScience
Teme:	Cellular physiology Cell biology Functional aspects of cell biology
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2589004221016874
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