X chromosome inactivation and Xist evolution in a rodent lacking LINE-1 activity.
Dosage compensation in eutherian mammals occurs by inactivation of one X chromosome in females. Silencing of that X chromosome is initiated by Xist, a large non-coding RNA, whose coating of the chromosome extends in cis from the X inactivation center. LINE-1 (L1) retrotransposons have been implicate...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2009-07-01
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| Serie: | PLoS ONE |
| Accesso online: | http://europepmc.org/articles/PMC2705805?pdf=render |
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