FOXO1 pathway activation by VISTA immune checkpoint restrains pulmonary ILC2 functions
Group 2 innate lymphoid cells (ILC2s) play a pivotal role in the development of airway hyperreactivity (AHR). However, the regulatory mechanisms governing ILC2 function remain inadequately explored. This study uncovers V-domain Ig suppressor of T cell activation (VISTA) as an inhibitory immune check...
Salvato in:
| Autori principali: | , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2025-02-01
|
| Serie: | The Journal of Clinical Investigation |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1172/JCI184932 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|