Activation of Peroxisome Proliferator-Activated Receptor γ by Rosiglitazone Inhibits Lipopolysaccharide-Induced Release of High Mobility Group Box 1

Peroxisome proliferator-activated receptors (PPARs) are shown to modulate the pathological status of sepsis by regulating the release of high mobility group box 1 (HMGB1), a well-known late proinflammatory mediator of sepsis. Ligand-activated PPARs markedly inhibited lipopolysaccharide- (LPS) induce...

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Autors principals:	Jung Seok Hwang, Eun Sil Kang, Sun Ah Ham, Taesik Yoo, Hanna Lee, Kyung Shin Paek, Chankyu Park, Jin-Hoi Kim, Dae-Seog Lim, Han Geuk Seo
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2012-01-01
Col·lecció:	Mediators of Inflammation
Accés en línia:	http://dx.doi.org/10.1155/2012/352807
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