Plasma Aβ42/40 predicts progression from Aβ-amyloid negative to positive PET scans

Background: The agreement between plasma Aβ42/40 and Aβ positron emission tomography (PET) is approximately 75 %, with ∼85 % of discrepancies due to positive plasma but negative PET results. It is unclear whether this reflects Aβ changes in plasma before PET-detectable. Objectives: To assess the inf...

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Principais autores:	Azadeh Feizpour, Vincent Doré, Pierrick Bourgeat, James D. Doecke, Rodrigo Canovas, Simon M. Laws, Tenielle Porter, Kun Huang, Christopher Fowler, Ralph N. Martins, Paul Maruff, Hamid R. Sohrabi, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Randall J. Bateman, Yan Li, Ovod Vitaliy, Larry Ward, Jurgen Mejan-Fripp, Colin L. Masters, Victor L. Villemagne, Christopher C. Rowe
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2026-02-01
סדרה:	The Journal of Prevention of Alzheimer's Disease
נושאים:	Plasma Aβ42/40 Aβ-amyloid PET Alzheimer’s disease Progression risk Primary prevention trial
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2274580725003966
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