Ataxin-2 is essential for cytoskeletal dynamics and neurodevelopment in Drosophila

Summary: Ataxin-2 (Atx2) is a highly conserved RNA binding protein. Atx2 undergoes polyglutamine expansion leading to amyotrophic lateral sclerosis (ALS) or spinocerebellar ataxia type 2 (SCA2). However, the physiological functions of Atx2 in neurons remain unknown. Here, using the powerful genetics...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Urko del Castillo, Rosalind Norkett, Wen Lu, Anna Serpinskaya, Vladimir I. Gelfand
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-01-01
Edice:	iScience
Témata:	Biological sciences Neuroscience Developmental neuroscience Cellular neuroscience Cell biology Developmental biology
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2589004221015078
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!