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Programmed conversion of hypertrophic chondrocytes into osteoblasts and marrow adipocytes within zebrafish bones

Much of the vertebrate skeleton develops from cartilage templates that are progressively remodeled into bone. Lineage tracing studies in mouse suggest that chondrocytes within these templates persist and become osteoblasts, yet the underlying mechanisms of this process and whether chondrocytes can g...

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Autori principali: Dion Giovannone, Sandeep Paul, Simone Schindler, Claire Arata, D'Juan T Farmer, Punam Patel, Joanna Smeeton, J Gage Crump
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2019-02-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/42736
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